WE DO IT ALL – Sewer & Drain Rodding Clean, Repair, Replace, Install
Offering complete underground plumbing services in Newcastle CA and will access your sewer lines and evaluate the problem before attempting to make any repairs. With a FREE ONSITE ESTIMATE, you’ll know exactly what your sewer repair & backup service will cost before any repairs are started. You will be advised on ways to avoid trying to fix your sewer lines yourself because a number of things could go wrong and make the problem worse. You might also be surprised how quickly and efficiently the expert plumbers work to get your sewer lines working properly.
FREE ONSITE ESTIMATES
Clogged drain and sewer lines cleared of all blockages. We clear every blockage. High Pressure water jet cleaning in Newcastle to keep drain and sewer lines free longer.
Video: Pipe Bursting Sewer Repair | Pipe Bursting Sewer Replace- Mr. Drain Plumbing
Video: Cheaper Than Dirt Sewer Repair Pt 3
6 Signals you might have a Sewer Problem in Newcastle CA:
- Bad odor coming out from floor drains
- Backed up / Clogged Toilets, Sinks, Showers, Bathtubs
- Overflowing Toilets
- Gurgling Toilet
- Basement Flooding
- Toilet paper appearing near downspouts
Common Newcastle Sewer Problems:
- Trees roots grow into main sewer lines
- Accumulation of Kitchen Grease / Oil being put down the drain
- Overflowing Toilets
- Feminine Hygiene Product Clogs
- Pipes Collapsing or Settling
- Underground Gas / Water Construction
We Do it All!
- Drain Rootering / Rodding
- Sewer Rodding
- Catch Basin Pumping
- Drain Repair
- Grease Trap Pumping
- Hydro Jetting Service – High Pressure Water
- Power Rodding
- Video Camera Inspection
- Preventative Maintenance
Newcastle disease is a contagious viral bird disease affecting many domestic and wild avian species; it is transmissible to humans. It was first identified in Java, Indonesia, in 1926, and in 1927, in Newcastle-upon-Tyne, England (whence it got its name). However, it may have been prevalent as early as 1898, when a disease wiped out all the domestic fowl in northwest Scotland. Its effects are most notable in domestic poultry due to their high susceptibility and the potential for severe impacts of an epizootic on the poultry industries. It is endemic to many countries.
Exposure of humans to infected birds (for example in poultry processing plants) can cause mild conjunctivitis and influenza-like symptoms, but the Newcastle disease virus (NDV) otherwise poses no hazard to human health. Interest in the use of NDV as an anticancer agent has arisen from the ability of NDV to selectively kill human tumour cells with limited toxicity to normal cells.
The causal agent, Newcastle disease virus (NDV), is a variant of avian paramyxovirus 1 (APMV-1), a negative-sense, single-stranded RNA virus. NDV/APMV-1 belong to the genus Avulavirus in the family Paramyxoviridae. Transmission occurs by exposure to faecal and other excretions from infected birds, and through contact with contaminated food, water, equipment, and clothing.
NDV strains can be categorised as velogenic (highly virulent), mesogenic (intermediate virulence) or lentogenic (nonvirulent). Velogenic strains produce severe nervous and respiratory signs, spread rapidly, and cause up to 90% mortality. Mesogenic strains cause coughing, affect egg quality and production, and result in up to 10% mortality. Lentogenic strains produce mild signs with negligible mortality.
In 1999, promising results were reported using an attenuated strain of the Newcastle virus, code named MTH-68, in cancer patients by researchers who had isolated the strain in 1968. It appears the virus preferentially targets and replicates in certain types of tumor cells, leaving normal cells almost unaffected. In 2006, researchers from the Hebrew University also succeeded in isolating a variant of the NDV, code named NDV-HUJ, which showed promising results in 14 glioblastoma multiforme patients. In 2011, Memorial Sloan–Kettering Cancer Center researchers found that NDV modified with the viral protein NS1 had a higher specificity for cancer cells that overexpressed the antiapoptotic factor Bcl-xL. The researchers suggested in cells that resist the normal inducement of apoptosis when infected will give NDV more time to incubate in cell and spread. Many cancer cells will overexpress antiapoptotic factors as part of tumor development. This mechanism of delaying apoptosis in abnormal cells gives NDV the specificity it needs to be an efficient cancer fighting oncolytic virus.